Dietary Influences of Evening Primrose and Fish Oil on the Skin of Essential Fatty Acid-Deficient Guinea Pigs
- 1 August 1987
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 117 (8) , 1360-1370
- https://doi.org/10.1093/jn/117.8.1360
Abstract
There have been reports that certain dietary lipids are capable of regulating cellular inflammation and hyperproliferation. To investigate further the role of dietary manipulation involving γ-linolenic acid (18:3n-6) and eicosapentaenoic acid (20:5n-3) on hyperproliferative cellular components, the effects of orally administered primrose oil (containing 18:3n-6) and menhaden fish oil (containing 20:5n-3) were tested in a cutaneous system using the essential fatty acid (EFA)–deficient guinea pig fed a hydrogenated coconut oil (HCO) diet. The effects of the dietary crossover regimen were determined on epidermalKeywords
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