Social Factors Affecting Emotionality and Resistance to Disease in Animals

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Abstract
Seven litters of Sprague-Dawley rats were permanently separated from their mothers at 15 days of age. Five control litters were weaned at the usual time of 21 days. At 45 days, animals were inoculated with Walker 256 carcinosarcoma cells. Mortality rate in the early-separated animals was significantly greater than that in the controls. These data increased the generality of the previously reported findings of an increased susceptibility to disease (gastric ulcers) in prematurely weaned rats.

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