Reductive Amination of Aldehydes and Ketones with Weakly Basic Anilines Using Sodium Triacetoxyborohydride
- 1 January 1990
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1990 (09) , 537-539
- https://doi.org/10.1055/s-1990-21991
Abstract
The weakly basic chloro-, nitro-, cyano-, ethoxy- carbonyl- and carboxy-substituted anilines react with aldehydes and ketones under reductive amination conditions, employing sodium triacetoxyborohydride, to give excellent yields of the corresponding secondary aromatic amines.Keywords
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