The Action of alpha-Chymotrypsin on Tyrosine Ethyl Ester.
- 1 January 1961
- journal article
- research article
- Published by Danish Chemical Society in Acta Chemica Scandinavica
- Vol. 15 (4) , 760-768
- https://doi.org/10.3891/acta.chem.scand.15-0760
Abstract
The splitting of tyrosine ethyl ester by [alpha]-chymotrypsin was studied by means of continuous titration in a pH-stat. The reaction was followed to about 99% hydrolysis, and to explain the obtained results it is necessary to assume the simultaneous or consecutive uptake of three molecules of substrate before reaction takes place. This supports the view that transpeptidation is the first step in the splitting of this substrate.This publication has 4 references indexed in Scilit:
- Steps in the reactions of chymotrypsin with tyrosine derivativesBiochemical Journal, 1959
- Contribution à l'étude cinétique de la protéolyse de la β-lactoglobuline par la trypsineBiochimica et Biophysica Acta, 1959
- The action of chymotrypsin on N-alkyl derivatives of phenylalanine ethyl esterBiochimica et Biophysica Acta, 1957
- PH DEPENDENCE OF THE AMINO ACID ESTERASE ACTIVITIES OF TRYPSIN AND CHYMOTRYPSIN1950