The effect of amphotericin B on the ultrastructure of Prototheca species
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Mycopathologia
- Vol. 76 (2) , 73-77
- https://doi.org/10.1007/bf00443753
Abstract
Prototheca zopfii and Prototheca wickerhamii strains were exposed to subinhibitory concentrations of the antimycotic amphotericin B, and the effect of the treatment on their ultrastructure was assessed. The results revealed ultrastructural changes in the treated cells, expressed by swelling of mitochondria, degradation of cell organelles, accumulation of microbody like structures, lipid droplets and starch granules in the cytoplasm, and changes in the inner layer of the cell wall.Keywords
This publication has 17 references indexed in Scilit:
- Ultrastructural study of Prototheca salmonis and comparison with known isolates of ProtothecaMycopathologia, 1980
- Medically Important YeastsAnnual Review of Microbiology, 1978
- An ultrastructural survey of the genus Prototheca with special reference to plastidsMycopathologia, 1977
- Susceptibility of Prototheca Species to Antifungal AgentsAntimicrobial Agents and Chemotherapy, 1976
- Antifungal drugsJournal of Antimicrobial Chemotherapy, 1975
- Protothecosis: A Critical ReviewAmerican Journal of Clinical Pathology, 1974
- PROTOTHECA: AN ALGA OR A FUNGUS?1Journal of Phycology, 1973
- Drug—induced alterations in the ultrastructural organization of Histoplasma capsulatum and Blastomyces dermatitidisMycopathologia, 1972
- Amphotericin B and Other Polyenic Antifungal AntibioticsAmerican Journal of Clinical Pathology, 1969
- Protothecosis, an Algal Infection: Report of a Case in ManJournal of Medical Microbiology, 1968