Risk of Selecting De Novo Drug-Resistance Mutations during Structured Treatment Interruptions in Patients with Chronic HIV Infection
Open Access
- 15 September 2005
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 41 (6) , 883-890
- https://doi.org/10.1086/432881
Abstract
Background. Structured treatment interruption (STI) may allow viral replication in the presence of decreased plasma drug levels, with risk of selection of resistance mutations.Keywords
This publication has 24 references indexed in Scilit:
- Therapeutic Immunization with Dendritic Cells Loaded with Heat‐Inactivated Autologous HIV‐1 in Patients with Chronic HIV‐1 InfectionThe Journal of Infectious Diseases, 2005
- Treatment for Adult HIV InfectionJAMA, 2004
- Emergence of Minor Populations of Human Immunodeficiency Virus Type 1 Carrying the M184V and L90M Mutations in Subjects Undergoing Structured Treatment InterruptionsThe Journal of Infectious Diseases, 2003
- Lack of persistent drug-resistant mutations evaluated within and between treatment interruptions in chronically HIV-1-infected patientsAIDS, 2003
- Structured Treatment Interruption in Patients with Multidrug-Resistant Human Immunodeficiency VirusNew England Journal of Medicine, 2003
- Long‐Cycle Structured Intermittent versus Continuous Highly Active Antiretroviral Therapy for the Treatment of Chronic Infection with Human Immunodeficiency Virus: Effects on Drug Toxicity and on Immunologic and Virologic ParametersThe Journal of Infectious Diseases, 2003
- A cytostatic drug improves control of HIV-1 replication during structured treatment interruptionsAIDS, 2003
- Platelet- and megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIVAIDS, 2003
- Virologic and Immunologic Consequences of Discontinuing Combination Antiretroviral-Drug Therapy in HIV-Infected Patients with Detectable ViremiaNew England Journal of Medicine, 2001
- Transient Mobilization of Human Immunodeficiency Virus (HIV)-Specific CD4 T-Helper Cells Fails To Control Virus Rebounds during Intermittent Antiretroviral Therapy in Chronic HIV Type 1 InfectionJournal of Virology, 2001