Development of a Standardized Analysis Strategy for Basic Drugs, Using Ion-Pair Extraction and High-Performance Liquid Chromatography PART IV. Application to Solid Pharmaceutical Dosage Forms
- 1 November 1983
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 6 (13) , 2521-2541
- https://doi.org/10.1080/01483918308064919
Abstract
The usefulness of two standardized HPLC-systems for the analysis of basic drugs in tablets and capsules is exemplified. The standardized HPLC systems both use a CN-column combined with either a polar or a non polar mobile phase. Also the sample preparationis standardized and simple; it involves suspension of the powder mixture in one of the mobile phase components, centrifugation and injection of the clear supernatant.This publication has 2 references indexed in Scilit:
- High-performance liquid chromatographic determination of papaverine in whole bloodJournal of Chromatography B: Biomedical Sciences and Applications, 1981
- Simultaneous Determination of Tetracaine and Its Degradation Product, p-n-Butylaminobenzoic Acid, by High-Performance Liquid ChromatographyJournal of Pharmaceutical Sciences, 1981