Effects of stimulus and response complexity on learning under bilateral spreading depression.

Abstract
Two experiments assessed effects of CS (conditioned stimulus) complexity and response difficulty on avoidance learning in control and bilateral spreading depression (BSD) rats. When 1, 2, or 3 elements acted as CS, BSD Ss were inferior to control Ss. For both groups, there was no difference between 2 or 3 element CSs, and both were superior to 1 element CS. When control and BSD Ss learned 1-way, 2-way, or shuttle avoidance, control Ss were superior to BSD Ss for all responses. Responses were significantly ordered for control Ss, 1-way being least difficult. There was no difference between 1-way and 2-way avoidance and both groups were superior to shuttle avoidance for BSD Ss.

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