Altered Calcium Homeostasis and Mitochondrial Dysfunction in Cortical Synaptic Compartments of Presenilin‐1 Mutant Mice
Open Access
- 1 March 1999
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 72 (3) , 1030-1039
- https://doi.org/10.1046/j.1471-4159.1999.0721030.x
Abstract
: Alzheimer's disease is characterized by amyloid β‐peptide deposition, synapse loss, and neuronal death, which are correlated with cognitive impairments. Mutations in the presenilin‐1 gene...Keywords
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