Expression Cloning of Gamma Interferon-Inducing Antigens ofMycobacteriumaviumsubsp.paratuberculosis
Open Access
- 1 June 2005
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 73 (6) , 3778-3782
- https://doi.org/10.1128/iai.73.6.3778-3782.2005
Abstract
Three recombinant proteins, Map10, Map39, and Map41, produced based on nucleotide sequences obtained from the screening of Mycobacterium avium subsp. paratuberculosis genomic library expressed in Escherichia coli significantly elicited gamma interferon production in peripheral blood mononuclear cells from infected cattle. Two of these proteins were members of the PPE protein family.Keywords
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