Rapid Effect of Sodium Cyanide and Dinitrophenol on Mammalian Nerve

24 March 1961

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 133 (3456) , 876-877
https://doi.org/10.1126/science.133.3456.876-a

Abstract

Strips of rat nerve from dorsal roots were immersed in solutions containing sodium cyanide and α-dinitrophenol. The inhibitors extinguish the action potential of such strips within minutes. The rapid action on mammalian nerve is contrasted with the slow effect of inhibitors on amphibian and invertebrate nerve.

Keywords

CYANIDES/PHARMACOLOGY
NITROPHENOLS/PHARMACOLOGY