Trimethoprim-Sensitivity Testing and Thymineless Mutants
- 1 May 1974
- journal article
- research article
- Published by Microbiology Society in Journal of Medical Microbiology
- Vol. 7 (2) , 143-153
- https://doi.org/10.1099/00222615-7-2-143
Abstract
Various laboratory media were examined for use in trimethoprim-sensitivity testing. The most suitable were Wellcotest Sensitivity Test Agar and Wellcome Nutrient Agar, because these were the least antagonistic to the action of trimethoprim. Thymine as well as thymidine were found to antagonise trimethoprim activity against wild-type bacteria, and both these compounds are absent from the above media.Keywords
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