A Peptidase (Aminopeptidase B) from Cat and Guinea Pig Liver Selective for N-Terminal Arginine and Lysine Residues. I. Purification and Substrate Specificity.

Publisher Website
Google Scholar
Abstract
An enzyme selectively hydrolyzing L-arginyl- and L-lysyl-[beta] -naphthyl-amides has been purified about 20-fold from cat and guinea pig liver and its characteristics have been studied. In all experiments comparisons were made with a highly purified rat liver aminopeptidase B preparation previously described. The enzyme preparation of each of the above species was shown to be free of esterase activity. L-Arginyl- and L-lysyl-[beta]-naphthylamide were hydrolyzed at similar rates by the three preparations. The substrate specificity hydrolytic characteristics described are similar to those of the previously reported rat liver aminopeptidase B preparation.

This publication has 0 references indexed in Scilit: