Final Report on the Aspirin Component of the Ongoing Physicians' Health Study
- 20 July 1989
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 321 (3) , 129-135
- https://doi.org/10.1056/nejm198907203210301
Abstract
The Physicians' Health Study is a randomized, double-blind, placebo-controlled trial designed to determine whether low-dose aspirin (325 mg every other day) decreases cardiovascular mortality and whether beta carotene reduces the incidence of cancer. The aspirin component was terminated earlier than scheduled, and the preliminary findings were published. We now present detailed analyses of the cardiovascular component for 22,071 participants, at an average follow-up time of 60.2 months.Keywords
This publication has 15 references indexed in Scilit:
- United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: interim resultsBMJ, 1988
- Randomised trial of prophylactic daily aspirin in British male doctorsBMJ, 1988
- Preliminary Report: Findings from the Aspirin Component of the Ongoing Physicians' Health StudyNew England Journal of Medicine, 1988
- The 2 × 2 factorial design: Its application to a randomized trial of aspirin and U.S. physiciansStatistics in Medicine, 1985
- Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel WallsNew England Journal of Medicine, 1979
- Aspirin and coronary deaths.Circulation, 1978
- A case-control study of regular aspirin use and coronary deaths.Circulation, 1978
- Design and analysis of randomized clinical trials requiring prolonged observation of each patient. I. Introduction and designBritish Journal of Cancer, 1976
- Regular aspirin use and myocardial infarction.BMJ, 1976
- Aspirin and coronary heart disease: findings of a prospective study.BMJ, 1975