Effect of High Hydrostatic Pressures on Colchicine-Damaged Mast Cells of Peritoneal Fluid.
- 1 June 1956
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 92 (2) , 328-331
- https://doi.org/10.3181/00379727-92-22467
Abstract
The abnormally shaped mast cells found in the peritoneal fluid of colchicine-treated rats are affected by the application of high hydrostatic pressure. The changes observed under pressure include rounding up of the cell, suggesting that the abnormal morphology is maintained by a strongly gelated cytoplasm. Induction of localized foci of gelation by colchicine is postulated to explain the formation of polymorphic mast elements.Keywords
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