Synthesis of a 3H-pyrido[1,2-b]pyridazin-3-one from pyridine N-imide and methylphenylcyclopropenone

Abstract
Pyridine N-imide (1a) reacts with methylphenylcyclopropenone (2) in methanol to give a β-aminoester (3) and the first reported 3H-pyrido[1,2-b]pyridazin-3-one (4); reaction in dichloromethane permitted isolation of the intermediate (5a).

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