Fungi in onychomycosis. A study by immunohistochemistry and dual flow cytometry

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Abstract
Aim To specify that different types of fungi attack the nails, and that they have different pathogenetic influences.Background There is still debate about the different pathogenicities of the different types of fungi which cause onychomycosis.Materials and Methods Histology, immunohistochemistry and dual flow cytometry were used to identify distinct fungi, including dermatophytes, yeasts and molds, in nail clippings.Results Various distinct fugi were confirmed responsible for nail infection, and these microorganisms were found morphologically indistinguishable from the pathogenic forms that invade other tissues and organs.Conclusion The term onychomycosis comprises a group of diseases of the nails caused by various distinct fungi.