Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-((2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino)benzoyl)-l-glutamic acid (CB3717), on human lymphoblastoid cells
- 1 December 1983
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 32 (24) , 3783-3790
- https://doi.org/10.1016/0006-2952(83)90150-8
Abstract
No abstract availableThis publication has 32 references indexed in Scilit:
- A potent antitumour quinazoline inhibitor of thymidylate synthetase: Synthesis, biological properties and therapeutic results in micePublished by Elsevier ,1981
- 5-Substituted quinazoline antifolatesPublished by Elsevier ,1980
- Quinazoline antifolates with dual biochemical loci of action. Biochemical and biological studies directed towards overcoming methotrexate resistancePublished by Elsevier ,1980
- Acquired methotrexate resistance in lymphoblasts resulting from altered kinetic properties of dihydrofoltate reductasePublished by Elsevier ,1977
- Factors determining cell sensitivity to methotrexate: Studies of folate and deoxyribonucleoside triphosphate pools in five mammalian cell linesPublished by Elsevier ,1974
- ACTIVE-SITE DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLATE REDUCTASEAnnals of the New York Academy of Sciences, 1971
- SITES OF ACTION OF AMETHOPTERIN: INTRINSIC AND ACQUIRED DRUG RESISTANCEAnnals of the New York Academy of Sciences, 1971
- Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitorsBiochimica et Biophysica Acta (BBA) - Enzymology, 1969
- Human lymphoblastoid lines from lymph node and spleenCancer, 1968
- THE INFLUENCE OF CYTOSTATIC TREATMENT ON SERUM LDH PATTERNS OF PATIENTS WITH BRONCHIAL CARCINOMA AND ITS RELATION TO TUMOR REGRESSIONAnnals of the New York Academy of Sciences, 1968