Pro/Con Debate of Activated Protein C in Severe Sepsis

This publication has 6 references indexed in Scilit:

• Drotrecogin alfa (activated) (recombinant human activated protein C) for the treatment of severe sepsis
  Critical Care Medicine, 2003
• Recombinant human activated protein C in sepsis: Inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials
  Critical Care Medicine, 2003
• Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock
  JAMA, 2002
• Intensive Insulin Therapy in Critically Ill Patients
  New England Journal of Medicine, 2001
• Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock
  New England Journal of Medicine, 2001
• Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome
  New England Journal of Medicine, 2000