ELECTROPHORESIS OF AUTOPROTHROMBIN AND BIOTHROMBIN
- 1 March 1956
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 34 (2) , 270-272
- https://doi.org/10.1139/o56-031
Abstract
Concentrates of biothrombin and autoprothrombin were prepared from purified prothrombin and subjected to electrophoresis. The mobility of biothrombin is less than that of prothrombin. The mobility of autoprothrombin is less than that of biothrombin. The biothrombin and autoprothrombin preparations examined were not electro-phoretically homogeneous. Prothrombin dissociates during electrophoresis at high voltage gradients. Since this does not occur with biothrombin and autoprothrombin, it seems likely that electrophor-etically homogeneous derivatives of prothrombin can be obtained with further purification work.Keywords
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