ACCUMULATION OF TC-99M-DIPHOSPHONATE IN 4 PATIENTS WITH HEPATIC NEOPLASM - CASE-REPORTS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 17  (12) , 1060-1061
Abstract
The accumulation of bone seeking radiopharmaceuticals in extraosseous lesions was reported in patients with myocardial infarction, cerebral infarction and some soft tissue tumors. While the precise mechanisms involved remain uncertain, the spectrum of abnormalities exhibiting such accumulation increases. 99mTc-Diphosphonate concentrated in 4 hepatic tumors (1 cholangiocarcinoma and 3 metastases from colon carcinoma). This property of phosphate-related radiopharmaceuticals was not reported previously. Awareness of the possibility of focal diphosphonate accumulation in the liver should help avoid confusion with right lower rib cage metastases or pleural effusion.

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