Phagocytosis of Particulate Complexes of γ-Globulin and Rheumatoid Factor
Open Access
- 1 April 1962
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 88 (4) , 519-525
- https://doi.org/10.4049/jimmunol.88.4.519
Abstract
Summary: Precipitates formed by the interaction of rheumatoid sera and fluorescent γ-globulin were ingested by viable leukocytes. This reaction required preliminary heating of the γ-globulin. The results suggest that the reactive portion of the γ-globulin is in the form of aggregates. The phenomenon of phagocytosis demonstrates a new biologic property of rheumatoid factor-γ-globulin precipitates and illustrates another resemblence of these precipitates to antigen-antibody complexes.Keywords
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