Deficiency of distal 8p —: report of two cases and review of the literature

Abstract
A terminal deletion in the short arm of chromosome 8 was found in a 2.5‐year‐old boy: 46,XY,del(8) (p22.0) and in a 1‐year‐old girl: 46,XX,del(8) (p23.1) with dysmorphic craniofacial features and developmental retardation. Erythrocyte GSR activities of the boy and of his parents were within normal limits. Vitamin K dependent coagulation factors in the girl and her parents gave normal results. Clinical findings were compared with previously reported cases and suggested a recognizable syndrome.