Glycolytic Enzymes in Adipose Tissue of Adult Diabetics
- 22 August 1970
- Vol. 3 (5720) , 444-445
- https://doi.org/10.1136/bmj.3.5720.444
Abstract
The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.Keywords
This publication has 9 references indexed in Scilit:
- A Defect of Glucose Utilization in Adipose Tissue of Adult Diabetics and in Some Conditions Which May Predispose to DiabetesClinical Science, 1970
- Defect in Glucose Utilization in Adipose Tissue of Patients with Maturity-onset DiabetesBMJ, 1969
- Effect of alloxan-diabetes on multiple forms of hexokinase in adipose tissue and lungBiochemical Journal, 1967
- New type of needle for obtaining large samples of human adipose tissueJournal of Lipid Research, 1967
- The effect of diabetes and insulin invivo and invitro on a low Km form of hexokinase from various rat tissuesBiochemical and Biophysical Research Communications, 1966
- THE EFFECT OF INSULIN ON HUMAN ADIPOSE TISSUECanadian Journal of Biochemistry, 1964
- ENZYME PATTERNS IN HUMAN TISSUES .2. GLYCOLYTIC ENZYME PATTERNS IN NONMALIGNANT HUMAN TISSUES1964
- INSULIN-RESISTANT DIABETES ASSOCIATED WITH INCREASED ENDOGENOUS PLASMA INSULIN FOLLOWED BY COMPLETE REMISSIONJournal of Clinical Investigation, 1961
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951