Three Unusual Trisomic Patterns in Children
- 1 March 1967
- journal article
- research article
- Published by American Medical Association (AMA) in American Journal of Diseases of Children
- Vol. 113 (3) , 322-328
- https://doi.org/10.1001/archpedi.1967.02090180082006
Abstract
EXTENSIVE data and increasingly diversified patterns have accumulated since the first reports of chromosomal trisomies in man.1-3Cytogenetic studies, in addition to helping establish new clinical entities such as the D and E trisomies, have also revealed cases with either double aneuploidy4or partial trisomy.5Furthermore, in certain cases, the autosomal trisomic pattern has been seen to affect only a proportion of the body cells (mosaics).6The following report deals with three rare cases of double, single, and partial trisomy, respectively. These patients, one of which was also a proven mosaic, serve to illustrate some aspects of the broadening spectrum of hyperdiploid states in man. Report of Cases Case1.—An infant girl (Fig 1) was delivered to a 21-year-old gravida 1 at 43 weeks gestation. The delivery was breech, and prolonged resuscitation was necessary. The birthweight was 1,700 gm (3 lb 12 oz), the crown-heel lengthThis publication has 0 references indexed in Scilit: