Catch-up Growth in Hypothyroidism

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Abstract
Growth is a complex process. It depends on an adequate nutritional substrate, stimulation by a variety of hormones, including growth hormone, thyroid hormones, and gonadal steroids, and mediation by growth factors such as the somatomedins, epidermal growth factor, fibroblast growth factor, and presumably others.1 , 2 Other hormones, such as insulin and vitamin D, exert important permissive effects.1 2 3 Fetal growth and growth during the first 6 to 12 months of extrauterine life appear to be dependent on growth factor and independent of hormones. Linear bone growth and bone maturation are modulated by growth hormone and thyroid hormones in childhood and by gonadal . . .