Ankyrin-bound fatty acid turns over rapidly at the erythrocyte plasma membrane.
Open Access
- 1 August 1987
- journal article
- research article
- Published by Taylor & Francis in Molecular and Cellular Biology
- Vol. 7 (8) , 2981-2984
- https://doi.org/10.1128/mcb.7.8.2981
Abstract
The membrane skeletal protein ankyrin was shown to be continuously acylated and deacylated with long-chain fatty acids in mature erythrocytes. At least a fraction of the lipid bound to ankyrin turned over rapidly (half-life, approximately 50 min) compared with the polypeptide backbone, which was stable throughout the erythrocyte life. This indicates a regulatory significance of the fatty acid modification for the function of ankyrin.This publication has 27 references indexed in Scilit:
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