Death from inside out: an overview
Open Access
- 30 August 1994
- journal article
- review article
- Published by The Royal Society in Philosophical Transactions Of The Royal Society B-Biological Sciences
- Vol. 345 (1313) , 237-241
- https://doi.org/10.1098/rstb.1994.0099
Abstract
Although a type of cell death strategically suited to participating in developmental processes has been well known for nearly thirty years, it is only in the recent past that the extraordinary ubiquity of such death has been appreciated. Apoptosis, a term first employed to describe such death defined in structural terms, is associated with a stereotyped set of effector processes, and is driven by genes most of which are familiar as oncogenes or oncosuppressor genes. Dysregulation of apoptosis leads to diseases of enormous social importance such as cancer and AIDS.Keywords
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