Enantioselective Synthesis of Cyclopentenones via Rhodium-Catalyzed Kinetic Resolution and Desymmetrization of 4-Alkynals
- 13 August 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (35) , 10296-10297
- https://doi.org/10.1021/ja0266161
Abstract
We have developed two new catalytic processes that provide efficient access to interesting chiral building blocks, cyclopentenones that bear tertiary and quaternary stereocenters, in high enantiomeric excess and very good yield. Structures such as these have potential utility in the synthesis of prostaglandins, pentenomycins, and related compounds.Keywords
This publication has 1 reference indexed in Scilit:
- Constant Selectivity Relationships of Addition Reactions of CarbanionsAngewandte Chemie International Edition in English, 2000