Folic acid-enhanced synergy for the combination of trimetrexate plus the glycinamide ribonucleotide formyltransferase inhibitor 4-[2-(2-Amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5,4,6][1,4]thiazin-6-yl)-(S)-ethyl]-2,5-thienoylamino-l-glutamic acid (AG2034): Comparison across sensitive and resistant human tumor cell lines

This publication has 24 references indexed in Scilit:

• Mechanisms of resistance to N-[5-[N-(3, 4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino]-2-thenoyl]-L-glutamic acid (ZD1694), a folate-based thymidylate synthase inhibitor, in the HCT-8 human ileocecal adenocarcinoma cell line
  Published by Elsevier ,2000
• Recent advances in the study of rTS proteins. rTS expression during growth and in response to thymidylate synthase inhibitors in human tumor cells
  Advances in Enzyme Regulation, 1997
• AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase
  Investigational New Drugs, 1996
• Biochemistry and pharmacology of glycinamide ribonucleotide formyltransferase inhibitors: LY309887 and lometrexol
  Investigational New Drugs, 1996
• New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening
  JNCI Journal of the National Cancer Institute, 1990
• Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines
  JNCI Journal of the National Cancer Institute, 1990
• Enzymes of salvage and de novo pathways of synthesis of pyrimidine nucleotides in human colorectal adenocarcinomas
  Biochemical Pharmacology, 1982
• Cultural and Antigenic Properties of Newly Established Cell Strains Derived From Adenocarcinomas of the Human Colon and Rectum
  JNCI Journal of the National Cancer Institute, 1974
• In Vitro Cultivation of Human Tumors: Establishment of Cell Lines Derived From a Series of Solid Tumors2
  JNCI Journal of the National Cancer Institute, 1973
• A new human cell line (FaDu) from a hypopharyngeal carcinoma
  Cancer, 1972