Aspergillosis

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Abstract
The spectrum of human disease caused by Aspergillus species includes hypersensitivity reactions, colonization syndromes, and invasive disease. Thus, it is one of the most interesting infectious agents encountered in humans, and its importance is underscored by recent autopsy studies that have noted an increasing incidence in immunocompromised hosts. The recognition and diagnosis of the various forms of aspergillosis are based on the clinical and radiographic patterns of disease. Treatment is based on the clinical syndrome; steroids are used in hypersensitivity illness, occasionally surgery for mycetomas complicated by bleeding, and antifungal pharmacotherapy in invasive disease. Outcome varies depending on the clinical syndrome.

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