RENAL GLUTAMINASE
- 1 September 1948
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 154 (3) , 542-548
- https://doi.org/10.1152/ajplegacy.1948.154.3.542
Abstract
The activity of renal glutaminase in tissue slices prepd. from frozen kidney cortex is significantly greater than that in extracts or homogenates of the same organ. The stimulation of the enzymatic activity in tissue slices by pyruvate and phosphate is marked. The greatest stimulation of renal glutaminase was obtained by a combination of phosphate and beta-hydroxybutyric acid. Possible relationship of this combination to the increased formation of urinary ammonia in diabetic acidosis is suggested.Keywords
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