COCCIDIOIDAL GRANULOMA

21 December 1912

journal article
research article
Published by American Medical Association (AMA) in JAMA

Vol. LIX (25) , 2253
https://doi.org/10.1001/jama.1912.04270140057022

Abstract

Up to this time eighteen cases of coccidioidal granuloma have been reported and traced to California, the seventeenth and eighteenth being reported by Brown¹of San Francisco, with review of the literature. The first case in California was discovered by Rixford²of San Francisco, and later described in conjunction with Gilchrist³of the Johns Hopkins Hospital Medical School. Afterward Ophüls⁴of San Francisco described the fungus with certain morphology and characteristics, giving the name ofOidium coccidioides, with report of thirteen cases, differentiating the fungus from the closely relatedBlastomyces coccidioidesof which much has been written, the latest article being by Hektoen⁵of Chicago. The mold appears to be of animal origin, though not proved, with occasional infection in man. Most infected persons came from the lower half of the San Joaquin valley, and were men employed in railway construction or in caring for

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