Autofluorescent granular cells in oral mucosal hyperplasias

Abstract
Four hyperplastic lesions of the human hard palate are described. They were characterized by the presence of an atrophic surface epithelium, an edematous matrix and the presence of large numbers of autofluorescent granular cells. There were also numerous mast cells. Histochemical and EM studies suggest that the granules are composed of lipofuscin. The pathogenesis of these lesions is discussed.

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