CD studies of conformational changes of DNA upon photosensitized UV-irradiation at 313 nm
- 1 February 1975
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 2 (2) , 179-184
- https://doi.org/10.1093/nar/2.2.179
Abstract
The role of thymine dimerization for previously reported U.V. induced confornational changes has been proved using acetophenone as sensitizer for the specific thymine dimerization upon irradiation at 313 nm. CD results demonstrate that formation of pyrimidine dimers cause typical conformational changes of the DHA B helix as observed on irradiation at 254 nm. Thus the primary role of adenine photoproducts may be excluded.Keywords
This publication has 2 references indexed in Scilit:
- ULTRAVIOLET‐LIGHT‐INDUCED CONFORMATIONAL CHANGES IN DNAPhotochemistry and Photobiology, 1973
- SPECIFIC FORMATION OF THYMINE DIMERS IN DNAPhotochemistry and Photobiology, 1969