Gastrointestinal effects of NSAIDs
- 1 November 1996
- journal article
- Published by Taylor & Francis in Postgraduate Medicine
- Vol. 100 (5) , 131-143
- https://doi.org/10.3810/pgm.1996.11.113
Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are well tolerated by the vast majority of patients. In a significant minority, however, gastrointestinal side effects may result in serious complications. Because these complications may be asymptomatic, physicians prescribing NSAIDs must weigh the analgesic and anti-inflammatory benefits of the drugs against their potential for causing adverse outcomes. In this article, the authors focus on the more common effects of the medications on the upper gastrointestinal tract.Keywords
This publication has 13 references indexed in Scilit:
- Future treatments for arthritis: New NSAIDs, NO NSAIDs, or No NSAIDs?Gastroenterology, 1995
- Long-term nonsteroidal anti-inflammatory drug use and gastroduodenal injury: The role of Helicobacter pyloriGastroenterology, 1992
- Management of Gastroduodenopathy Associated With Use of Nonsteroidal Anti-Inflammatory DrugsMayo Clinic Proceedings, 1992
- Risk for Serious Gastrointestinal Complications Related to Use of Nonsteroidal Anti-inflammatory DrugsAnnals of Internal Medicine, 1991
- Long-term nonsteroidal antiinflammatory drug use and Helicobacter pylori infectionGastroenterology, 1991
- Corticosteroid Use and Peptic Ulcer Disease: Role of Nonsteroidal Anti-inflammatory DrugsAnnals of Internal Medicine, 1991
- Ranitidine in the treatment of non-steroidal anti-inflammatory drug associated gastric and duodenal ulcers.Gut, 1991
- Nonsteroidal Anti-inflammatory Drug Use and Increased Risk for Peptic Ulcer Disease in Elderly PersonsAnnals of Internal Medicine, 1991
- Effect of Omeprazole and Ranitidine on Ulcer Healing and Relapse Rates in Patients with Benign Gastric UlcerNew England Journal of Medicine, 1989
- Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration.Gut, 1987