Effect of Diets Containing Varying Concentrations of Essential Fatty Acids and Triglycerides on Renal Function in Uremic Rats and NZB/NZW F1 Mice
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 38 (4) , 233-237
- https://doi.org/10.1159/000183315
Abstract
Influences of essential fatty acids (EFA) and triglycerides as reasons for the progression of chronic renal failure are still in debate. We studied the outcome of four diets containing different concentrations of triglycerides and EFA in 5/6 nephrectomized rats and in NZB/W mice up to 45 weeks. The results showed no significant differences in the outcome of survival rate, proteinuria, urea, and creatinine levels as well as histological findings in the different groups of both animal models. We conclude that diets containing EFA up to C18:2 or being free of EFA or that triglyceride-enriched diets have no influence on the natural course of the renal disease in these both experimental models.Keywords
This publication has 1 reference indexed in Scilit:
- Prevention of Glomerulonephritis and Prolonged Survival in New Zealand Black/New Zealand White F1 Hybrid Mice Fed an Essential Fatty Acid-deficient DietJournal of Clinical Investigation, 1981