Comparison of human fecal and serum parvo-like viruses

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Abstract
Parvovirus-like particles found in the sera of 2 blood donors had the EM size and appearance of a virus (B19) found in the serum of another blood donor and a virus in the feces of a normal subject. Antibody to these viruses was detected by immune EM and immunoelectro-osmophoresis in the sera of 50 children 10-15 yr old. Of these, 36% had antibody to the fecal virus, 36% had antibody to B19 and 54% had antibody to the 2 other serum viruses. Serologically the 3 serum viruses were similar, but the fecal virus was distinct. The 2 blood donors had nonspecific symptoms at the time of viremia. Both had immunoglobulin M antibody to the virus when tested 3.5 and 4.5 wk later, but no viruses were detected in the feces or urine.