Physical mapping of genes and sequences at the end of the human X chromosome short arm
- 1 May 1987
- journal article
- Published by Wiley in Annals of Human Genetics
- Vol. 51 (2) , 137-143
- https://doi.org/10.1111/j.1469-1809.1987.tb01055.x
Abstract
Human-rodent somatic cell hybrids containing deleted and translocated human X chromosomes have been used to map genes and sequences in and around the pseudoautosomal region. The following order was found: (DXS69, DXS70, DXS143)-(DXS31, STS)-MIC2. This order is consistent with the known inheritance patterns of DXS31, STS and MIC2. Assuming that the translocations and deletions we have studied are not complex rearrangements, we conclude that the pseudoautosomal region consists of less than 5 X 10(6) bp of DNA.Keywords
This publication has 27 references indexed in Scilit:
- Hypervariable telomeric sequences from the human sex chromosomes are pseudoautosomalNature, 1985
- Construction of a human X-chromosome-enriched phage library which facilitates analysis of specific lociGene, 1985
- Inherited Chondrodysplasia Punctata Due to a Deletion of the Terminal Short Arm of an X ChromosomeNew England Journal of Medicine, 1984
- On the nature and extent of XY pairing at meiotic prophase in manCytogenetic and Genome Research, 1984
- Single-copy DNA sequences specific for the human Y chromosomeNature, 1983
- Genetic evidence that a Y-linked gene in man is homologous to a gene on the X chromosomeNature, 1983
- DNA Content and DNA-Based Centromeric Index of the 24 Human ChromosomesScience, 1973
- Cytological Evidence for the Association of the Short Arms of the X and Y Chromosomes in the Human MaleNature, 1971
- Definitive Evidence for the Short Arm of the Y Chromosome associating with the X Chromosome during Meiosis in the Human MaleNature, 1970
- The genetical and mechanical properties of the sex-chromosomesJournal of Genetics, 1934