A GENERAL SYNTHESIS OF NEW DITHIOLETHIONE DERIVATIVES: 5-(1-HYDROXYIMINO ALKYL)-1,2-DITHIOLE-3-THIONES AND 5-ACYL-I,2-DITHIOLE-3-THIONES

Abstract
The synthesis of 5-(1-hydroxyiminoalkyl)-1,2-dithiole-3-thiones by allowing 5-alkyl-1,2-dithiole-3-thiones to react with an excess of sodium nitrite in acetic acid and by reducing highly insoluble intermediate disulfides by sodium sulfide in a DMSO-water mixture is described. 5-(1-hydroxyimino)-1,2-dithiole-3-thiones are easily transformed into 5-acyl-1,2-dithiole-3-thiones. All yields are quite satisfactory.