THE INFLUENCE OF VARIOUS FACTORS UPON INTESTINAL ABSORPTION INVOLVING OSMOTIC WORK IN THE UNANESTHETIZED DOG

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Abstract
The authors trained dogs in which chronic Thiry-Vella loops had been previously prepared. By use of such preps. for waking-dog absorption expts., chloride ion, in the presence of sulfate, is absorbed against a steep gradient, and more rapidly than previously reported for acute expts. on anesthetized dogs. This chloride impoverishment occurs most rapidly low in The ileum, and progressively more slowly in high segments of the small gut. Excitement interferes with impoverishment of chloride by low ileal segments of intestine. Suggestion of blood was not found to alter absorption rates beyond the limits of intra-individual variability.