Clostomicins, new antibiotics produced by Micromonospora echinospora subsp. armeniaca subsp. nov. I Production, isolation, and physico-chemical and biological properties.

1 January 1986

journal article
research article
Published by Japan Antibiotics Research Association in The Journal of Antibiotics

Vol. 39 (10) , 1407-1412
https://doi.org/10.7164/antibiotics.39.1407

Abstract

A soil isolate named as Micromonospora echinospora subsp. armeniaca, subsp. nov. KMR-593 was found to produce at least five related antibiotics, clostomicins, active against Gram-positive bacteria including anaerobes. From the physico-chemical properties, one of these components was identified with lipiarmycin and others were found to be new antibiotics. Each component includes two chlorine atoms and the molecular weights of A and B2, C, and D are 1,058, 1,042 and 1,056, respectively. The structural differences were characterized by NMR analyses.

This publication has 1 reference indexed in Scilit:

Structural studies on lipiarmycin I. Characterization by 1H and 13C NMR spectroscopy and isolation of methyl 2-O-methyl-4-O-homodichloroorsellinate-.BETA.-rhamnoside.
The Journal of Antibiotics, 1983