CELL-SPECIFIC CYTO-TOXICITY EXPRESSED BY A CONJUGATE OF RICIN AND MURINE MONOCLONAL-ANTIBODY DIRECTED AGAINST THY 1.1 ANTIGEN
- 1 January 1981
- journal article
- research article
- Vol. 41 (10) , 3913-3917
Abstract
The isolation and characterization of a conjugate of ricin1 and a Thy 1.1-specific monoclonal IgG2a murine antibody synthesized using N-succinimidyl-3-(2-pyridyldithio)propionate are described. The conjugate selectively inhibited protein synthesis in Thy 1.1-positive (AKR SL3) mouse leukemia cells compared to Thy 1.2-positive (AKR/Cu SL1) cells.This publication has 11 references indexed in Scilit:
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