Estrogen‐induced changes in the golgi apparatus and lipid of the uterine epithelium of the rat in the normal cycle

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Abstract
The Golgi apparatus of the uterine epithelium of the rat starts to increase in size during the transition from diestrus to proestrus and continues to enlarge until it reaches its maximum development in estrus. Regression takes place during metestrus. The accumulation of phospholipid at the base of the epithelial cell, characteristic of diestrus, decreases in quantity as the Golgi apparatus increases in size and reappears as the Golgi apparatus regresses. Both of these changes are responses to circulating estrogen and form part of the complex series of reactions by means of which this hormone exercises its control over reproductive function.