Ovulation Induced by Hypothalamic Stimulation in the Anesthetized Rat

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Abstract
In the present study, employing 38 female rats with normal estrous cycles, electrical stimulation during pentobarbital anesthesia was effective in inducing ovulation. It was found that bilateral stimulation of the hypothalamus in anesthetized proestrous rats during the ‘critical period’ and within certain spatial and current limitations consistently caused ovulation. The area that appears most responsive is medially situated in the ventral hypothalamus, between the optic chiasma and the infundibular stalk.