Treatment of Acute Massive Digitalis Poisoning by Administration of a Chelating Agent

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Abstract
THE heightened sensitivity of the diseased myocardium to digitalis, as manifested by toxic responses to average or small doses, is well established.1 Chelating compounds that act by removing calcium from the ionic milieu have been useful in the treatment of digitalis intoxication in patients with heart disease.2 A recent abortive suicidal attempt permitted us to observe the effects of huge doses of orally administered digoxin on the normal heart and its response to therapy with a chelating agent.Case ReportL.Z., a 49-year-old single woman, was admitted to the Maimonides Hospital on October 11, 1958, 1 day after ingesting 100 . . .