Induction of Melanotic Tumors in the Syrian Golden Hamster After Administration of Ethyl Carbamate23
- 1 September 1960
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 25 (3) , 627-630
- https://doi.org/10.1093/jnci/25.3.627
Abstract
Ethyl carbamate (urethan), when given as 0.2 percent solution in drinking water to female and male Syrian golden hamsters, induced in the males a high incidence of melanotic tumors similar to those elicited in this species by 7,12-dimethylbenz[a]anthracene (DMBA). In both sexes a high incidence of papilloma of the forestomach was also observed. Cutaneous applications of 20 percent urethan failed to show a tumorigenic effect.Keywords
This publication has 4 references indexed in Scilit:
- STUDIES OF SKIN CARCINOGENESIS IN THE SYRIAN GOLDEN HAMSTER1960
- The Action of N-2-Fluorenylacetamide in the Syrian Golden Hamster2JNCI Journal of the National Cancer Institute, 1959
- The experimental production of kerato‐acanthomas in the hamster and the mouseThe Journal of Pathology and Bacteriology, 1959
- URETHAN (ETHYL CARBAMATE) AS A MULTIPOTENTIAL CARCINOGEN1958