Association of hydroxamate siderophore (aerobactin) with Escherichia coli isolated from patients with bacteremia
- 1 December 1984
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 46 (3) , 835-838
- https://doi.org/10.1128/iai.46.3.835-838.1984
Abstract
Clinical isolates of Escherichia coli were examined for the presence of hydroxamate siderophore (aerobactin). The incidence of aerobactin-positive strains of E. coli from the blood was greater than the incidence of these strains isolated from other sites. The presence of aerobactin and the virulence of strains of E. coli in urinary tract infection were also examined in mice. The presence of aerobactin in the strains of E. coli correlated with virulence as measured by proportion of deaths but not with renal infection. These results suggest that the presence of aerobactin may be a significant factor in the invasion of the blood stream.This publication has 18 references indexed in Scilit:
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