Distrust, Race, and Research

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Abstract
DISPARITIES IN health, health care, and health outcomes have been documented extensively in the public health and biomedical literature. In an effort to better understand disparities in health and to improve the generalizability of research findings, federal agencies have mandated that minorities be adequately represented in all clinical research.1 Despite awareness of the ethical and scientific underpinnings of this mandate, investigators have voiced their concerns about successfully recruiting minority groups into clinical studies.2,3 A widespread concern is that distrust of research and the medical community will impede successful recruitment of African Americans and other minority groups.