Immunoelectrophoretic investigations of blood serum proteins in muscular diseases

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Abstract
Sera of patients with Duchenne progressive muscular dystrophy and their mothers and sera of patients with neurogenic muscular atrophy show changes in protein fractions. In Duchenne dystrophy a genetic protein abnormality in the form of changes in [beta]1 -globulins occurred when the diagnostic serum ADSR was used. In neurogenic muscular atrophy the raised level of [alpha]2-globulins, which may depend on atrophy of the muscle, corresponded to the larger number of precipitation arcs obtained in immunoelectrophoresis with the specific diagnostic serum AWHSR.